RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Mdm4
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; ELISA; Flow Cytometry etc.
Target
Trp53
Pathway
Mdm4-p53 pathway
PubMed ID
Title
Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice
Year
2021
Function
"In this study, we found that mouse double minute 4 homolog (MDM4) is highly expressed in the fibrotic lesions of human IPF and experimental pulmonary fibrosis in aged mice."